Amixide-H Tablet - Uses, Dosage, Side Effects, Price, Composition | Practo (2024)

Allergy

This medicine is not recommended for use in patients with a known allergy to amitriptyline, chlordiazepoxide, any medicine belonging to either the benzodiazepine or tricyclic antidepressants class, or any other ingredients present in the formulation.

Monoamine oxidase inhibitors (MAO)

This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between stopping therapy with MAOIs and starting therapy with this medicine.

Acute myocardial infarction

This medicine is not recommended for use in patients who have had an episode of heart-attack in recent times or recovering from it.

Severe Cardiovascular Disorders

This medicine is not recommended for use in patients who are suffering from severe heart diseases or any conditions that prolong QT interval due to the increased risk of worsening of the patient's condition.

Angle Closure Glaucoma

This medicine is not recommended for use in patients with angle-closure glaucoma due to the increased risk of worsening of the patient's condition.

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Driving or Operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Hypotension

Use of this medicine may increase the risk of fall in blood pressure, and hence, caution is advised. Regular monitoring of blood pressure is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Bipolar Disorder

This medicine should be used with extreme caution in patients suffering from bipolar disorder due to the increased risk of worsening the patient's condition. Consult your doctor and report the incidence of bipolar depression or mania before receiving this medicine. An alternative treatment option should be considered in some cases based on the clinical condition.

Suicidal tendencies

This medicine should be used with caution due to the increased risk of suicidal tendencies. This risk is especially higher in young adult patients. Patients should be closely monitored for any change in mood or behavior. Report any such incidence to the doctor so that counseling and monitoring of progress can be performed at regular intervals. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Benign Prostatic Hyperplasia

This medicine should be used with caution if you have an enlarged prostate gland due to the increased risk of worsening the condition. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Withdrawal symptoms

Abrupt discontinuation of this medicine may increase the risk of adverse effects, especially if you have been using a high dose for a long duration. A gradual dose reduction is recommended to avoid these reactions. Do not stop the use of this medicine without consulting your doctor.

Other medicines

Amixide-H Tablet may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Sugeries

Use of this medicine is not recommended if you are planning to undergo a surgery in near future. Consult your doctor in this regard so that it can be discontinued properly.

Thyroid disorders

This medicine should be used with extreme caution in patients having a disorder of the thyroid gland due to the increased risk of worsening the condition. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol with this medicine is not recommended as it increases the risk of side effects like dizziness, difficulty in concentration. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.

This medicine should be used with caution in patients suffering from heart disease like heart failure, stroke, heart block etc due to the increased risk of adverse effects. A fall in blood pressure, changes in the pulse, dizziness and other associated complications should be reported to the doctor on priority. It is advised to not take this medicine if the patient has recently suffered a heart attack. An alternative treatment option should be considered in some cases based on the clinical condition.

This medicine should be administered with extreme caution in patients suffering from Pheochromocytoma, the risk of severe to fatal change in blood pressure is very high. You may require a dose adjustment and more frequent clinical monitoring to safely use this medicine. An alternative treatment option should be considered in some cases based on the clinical condition.

This medicine should be used with caution in patients who are suffering from seizures due to the increased risk of worsening of the condition. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

This medicine should be used with caution if you have diabetes as the risk of changes in blood sugar levels are very high. You should get your blood sugar levels checked more frequently while using this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

This medicine should be used with caution if you have glaucoma. Use of this medicine can worsen the symptoms of both closed and open-angle glaucoma. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

This medicine should be used with caution in patients who are suffering from kidney diseases due to the increased risk of adverse effects. Regular monitoring of the kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

This medicine should be used with caution in patients who are suffering from liver diseases due to the increased risk of adverse effects. Regular monitoring of the liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Information not available.

Information not available.

Category

Psychotherapeutic combinations

Schedule

Schedule H

[Internet]. Mylan.com. 2018 [cited 13 August 2018]. Available from:

http://www.mylan.com/-/media/pds/documents/us/mg-cdam-r1mh.pdf

[Internet]. Accessdata.fda.gov. 2018 [cited 13 August 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/016949s038lbl.pdf

Chlordiazepoxide and Amitriptyline Hydrochloride (amitriptyline hydrochloride/chlordiazepoxide) dose, indications, adverse effects, interactions... from PDR.net [Internet]. Pdr.net. 2018 [cited 13 August 2018]. Available from:

http://www.pdr.net/drug-summary/Chlordiazepoxide-and-Amitriptyline-Hydrochloride-amitriptyline-hydrochloride-chlordiazepoxide-3030

DailyMed - CHLORDIAZEPOXIDE AND AMITRIPTYLINE HYDROCHLORIDE- chlordiazepoxide and amitriptyline hydrochloride tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 13 August 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=66a756f2-ac77-451c-a19a-08896d73b15c